By blocking NNMT activity, it increases critical cellular metabolites (SAM, NAD) that drive downstream increases in energy expenditure and metabolic health 1-4
The injections are painless
Based on current clinical evidence, the rough ordering from largest to smallest weight-loss effect is: Tirzepatide highest average weight loss Semaglutide significant weight loss Tesamorelin moderate weight loss, primarily through visceral fat reduction AOD-9604 primarily body composition effects MOTS-c primarily metabolic and energy effects rather than pure weight reduction AOD-9604 and MOTS-c are generally not considered replacements for GLP-1 medications in patients seeking substantial weight reduction
what not to do after a B12 injection - Do not start another intramuscular injection without clinician advice
Vitamin B12 injections are generally considered to be very safe
For individuals who want visceral fat reduction without the systemic growth hormone effects, or who have contraindications to growth hormone elevation, AOD-9604 may be preferable